Novi Cost Breakdown: What You Actually Pay Per Month in 2026

By HollyHerman.com Wellness Team | Updated May 2026

This article is for informational purposes only and is not medical advice. Pricing details are based on Novi's publicly available materials as of the date of publication and are subject to change. Always confirm current pricing directly with the platform before signing up.

If you've spent any time pricing out telehealth GLP-1 programs, you've probably noticed something: nobody quite tells you the real number you're going to pay over the first three months. The “starting at” prices are everywhere. The actual all-in cost — what hits your card on day one and what your account balance looks like ninety days later — is harder to find. So let me lay out the actual Novi math, in actual dollars, with the actual Terms of Service rules applied.

The short version: Novi's “starting at” pricing is real, but the 3-month minimum commitment changes the calculation in a way that matters. If you're deciding between platforms, you need to compare 3-month commitment totals, not month-one promotional prices. Here's how the numbers actually work.

Novi's Published Monthly Prices

Per Novi's homepage and Terms of Service, the published monthly starting prices are:

Compounded semaglutide: $174 per month (positioned as the most affordable option, same active ingredient as Ozempic and Wegovy)

Compounded tirzepatide: $283 per month (positioned as the most popular option, same active ingredient as Mounjaro and Zepbound)

These prices are all-inclusive, meaning they cover the medical consultation, the medication itself, the injection supplies needed for self-administration, and ongoing access to the care team for check-ins and dose adjustments. There are no separate consultation fees, no membership fees, and no surprise charges for follow-up communications. That structure is genuinely cleaner than platforms that charge separately for consultations, refills, or “premium” support tiers.

The price difference between semaglutide and tirzepatide reflects the cost difference in the active pharmaceutical ingredients themselves — tirzepatide is more expensive to compound because the active ingredient is more expensive. The same price gap exists across compounded GLP-1 telehealth in general.

The 3-Month Commitment Math

This is where the real cost analysis begins. Novi's Terms of Service explicitly state: “By enrolling in Subscription Services, you agree to pay for a minimum of three (3) consecutive months of Service. For these Products and Services, your payment account will be automatically charged as described for that Product or Service.”

The Terms further specify that the first month's fee plus the monthly fee for the following two months is charged at the time of purchase and is non-refundable, unless the clinician determines the prescription is not medically appropriate for you (in which case the initial payment is refunded).

What that means in practice:

Compounded semaglutide on Novi: $174 × 3 = $522 commitment up front

Compounded tirzepatide on Novi: $283 × 3 = $849 commitment up front

This is the number that should drive your decision, not the $174 and $283 figures on the homepage. If your budget can absorb $522 to $849 right now, the math works out fine and the per-month rate is reasonable. If you're thinking “I'll try one month and decide whether to continue,” Novi is structurally not built for that. The Terms are clear and the company explicitly notes they will defend chargeback disputes from customers attempting to exit the 3-month commitment.

For context on whether GLP-1 therapy is even a fit for your clinical situation before you commit to that up-front spend, read my guide to how compounded GLP-1 works.

How Novi Compares to Brand-Name Retail

Even with the 3-month commitment factored in, Novi's pricing represents a significant savings versus brand-name retail without insurance. Here are the comparison numbers.

Brand-name Wegovy (FDA-approved semaglutide for chronic weight management) retails around $1,349 per month without insurance. Three-month total: $4,047. Novi compounded semaglutide three-month total: $522. Difference: $3,525 over the first three months, or roughly an 87 percent reduction.

Brand-name Zepbound (FDA-approved tirzepatide for chronic weight management) retails around $1,069 per month without insurance. Three-month total: $3,207. Novi compounded tirzepatide three-month total: $849. Difference: $2,358 over the first three months, or roughly a 74 percent reduction.

For most uninsured patients, the savings are real. Even for insured patients who face the typical $200 to $400 monthly copay after prior authorization, Novi tends to come in lower over a 3-month period. The trade-off is the regulatory distinction between FDA-approved brand-name medication and compounded medication that has not been individually FDA-evaluated. That distinction is real and worth understanding before deciding what your money is buying.

Does Novi Take Insurance?

Per Novi's published materials, all Novi prescriptions are cash-pay. The company notes that insurance may reimburse patients for branded options when applicable, and the compounded medications are intentionally priced to be affordable without insurance. In practice this means you pay Novi directly, and any insurance reimbursement happens (if at all) on the back end through your own claims submission.

HSA and FSA acceptance was not specifically addressed in the publicly available materials I reviewed. If pre-tax payment is important to you, contact Novi directly to confirm before signing up. The compounded medication category in general has mixed acceptance for HSA/FSA — some platforms accept these, others don't.

What's Actually Included in the Monthly Fee

Per Novi's Terms of Service and homepage, the monthly fee covers:

The medication itself — a 4-week supply of compounded semaglutide or compounded tirzepatide at the dose your prescribing clinician determines is appropriate, with dose escalation following standard GLP-1 titration protocols.

The injection supplies needed for self-administration. Most patients self-inject weekly using subcutaneous injection in the abdomen, thigh, or upper arm.

The independent physician consultation fee, which the Terms list at $20 per month going to the affiliated independent medical group. This is bundled into the headline price rather than billed separately.

Ongoing access to the care team for check-ins, dose adjustments, side-effect support, and questions. Novi specifically advertises unlimited support from clinicians at no additional cost.

Coaching support at no additional cost. The level and structure of coaching wasn't fully detailed in the public materials I reviewed, but the inclusion of coaching is positioned as a differentiator versus more bare-bones telehealth platforms.

Free 2-day shipping per the homepage marketing. Shipping was the one item with the most marketing emphasis and the least Terms of Service detail, so worth confirming current shipping turnaround at signup.

What Costs More Beyond the Subscription

The Terms of Service note that customers are responsible for any applicable sales, use, duty, customs, or other governmental taxes due with respect to the purchase, plus shipping and handling charges shown at the time of purchase. For most domestic U.S. customers these are minimal additions, but they do exist.

If you fill a prescription with a pharmacy outside Novi's network — for example, if you're prescribed something through Novi's clinician that isn't dispensed through their compounding pharmacy partner — Novi sends the prescription to your pharmacy of choice, but you're then responsible for paying that pharmacy directly for the medication. This isn't a common scenario for the compounded GLP-1 use case, but it's worth knowing exists in the Terms.

Cancellation Cost Math

You can cancel your Novi subscription at any time after the 3-month commitment is fulfilled. The cancellation must occur at least 15 days before the next billing date to prevent the next month's charge. If you cancel within the cancellation window, your card stops being charged the following month.

Once a prescription has been dispensed or shipped, it cannot be returned or refunded. This is a category-wide rule for compounded medications, not a Novi-specific policy. The dispensed medication is yours.

The implication for cost planning: if you complete your 3-month commitment ($522 for semaglutide, $849 for tirzepatide), find that GLP-1 therapy isn't producing the results you expected, and want to discontinue, your total cost is the 3-month commitment plus whatever monthly fees process before your cancellation takes effect. There's no penalty for cancellation after month three, but timing the cancellation right is on you.

The Refund Eligibility Window

The one cost-recovery scenario worth understanding is the medical-eligibility refund. If you complete the intake quiz, pay the initial fee, and Novi's clinician determines after review that you are not appropriate for prescription GLP-1 treatment, your initial payment is refunded. This is per the Terms of Service.

For context, the categories of patients who are most commonly declined include those with personal or family history of medullary thyroid carcinoma, those with Multiple Endocrine Neoplasia syndrome type 2, those with significant pancreatitis history, those who are pregnant or breastfeeding, and those whose BMI does not meet clinical criteria. If any of these apply to you, you should expect the medical screening to flag the issue. The refund mechanism exists precisely for that scenario.

For a more detailed look at GLP-1 contraindications and the medical screening criteria that determine eligibility, see my GLP-1 side effects in women guide.

Hidden Costs Most Reviews Don't Discuss

The medication price is one component of GLP-1 weight loss treatment, but it isn't the full clinical cost. A few additional spends that are worth budgeting for:

Lab work. While Novi's intake doesn't appear to require pre-treatment labs based on the public materials, many clinicians recommend baseline metabolic panel, lipid panel, and HbA1c testing before starting GLP-1 therapy and at intervals during treatment. If you don't have insurance covering routine labs, this can add $100 to $300 per round through direct-to-consumer lab services.

Protein supplementation. GLP-1 treatment typically results in significantly reduced food intake, which means hitting the recommended 1.2 to 1.6 grams of protein per kilogram of body weight from food alone gets harder. Most patients add a protein powder or shake to their daily routine to protect lean muscle mass during weight loss. Budget $30 to $60 per month.

Hydration and electrolytes. Reduced food intake on GLP-1 also means reduced fluid intake from food. Many patients add electrolyte supplementation to manage early-treatment symptoms. Budget $15 to $30 per month.

Resistance training. Not a direct dollar cost if you're already exercising, but if you're not, this is essentially required during GLP-1 treatment to preserve lean muscle. Budget either gym membership cost or basic home equipment ($100 one-time for adjustable dumbbells, etc.).

None of these are specific to Novi. They apply across all GLP-1 treatment regardless of platform. But they do affect the total cost of doing GLP-1 weight loss correctly.

Novi vs Other Compounded GLP-1 Platforms

For a side-by-side cost comparison of Novi against MEDVi, TrimRx, and AgelessRx — the three other compounded GLP-1 telehealth platforms I've reviewed in detail — see the full Novi vs MEDVi vs TrimRx comparison. Each platform has distinct positioning and the right answer depends on your priorities (lowest cost, most clinical support, longevity-broader catalog, etc.).

For background on what compounded GLP-1 actually is and how it differs from brand-name FDA-approved versions, see my how compounded GLP-1 works piece. For the broader Novi review covering provider directory, sourcing, and the user experience, see the main Novi review.

The Bottom Line on Cost

Novi's pricing is real. $174 per month for compounded semaglutide and $283 per month for compounded tirzepatide is competitive in the compounded telehealth GLP-1 category. The all-inclusive monthly structure (no separate consultation, refill, or membership fees) is cleaner than several competitors. The savings versus brand-name retail are significant.

The number that matters for your decision is the 3-month commitment total: $522 for semaglutide, $849 for tirzepatide. Plan for that as your day-one outlay. Add $100 to $200 per month for the supporting protein, electrolytes, and lab work that protect your outcome. The total first-3-months cost lands somewhere around $750 to $1,300 depending on medication and how you handle the supporting nutrition. Versus brand-name retail, that's still a significant savings.

If your budget supports the 3-month commitment and your clinical situation is appropriate for GLP-1 therapy, Novi's pricing math works. If you need the option to test for one month and exit, this isn't structurally the platform for that — and reading the Terms of Service before signing up is the right way to confirm the commitment is one you can absorb.

Editorial note: All pricing referenced in this article is based on Novi's publicly available materials as of the date of publication. Pricing is subject to change. Compounded semaglutide and compounded tirzepatide are not FDA-approved for safety, effectiveness, or quality. This article is for informational purposes only and does not constitute medical advice or financial advice.